No difference in temperment. A snake is a snake. A WC snake can become accustom to you and learn not to fear you, just as any CB snake can. But as was already mentioned, WC snakes nearly always carry a parasite load. It can range from mild and having no apparent effect on the snake, to a heavy load which may include tapeworms and effects the snake's appetite, body mass, and immunity. Garters can live for many years while carrying a parasite load, but the bottom line is, they are much better off without the parasite load.

If you're brave enough to try it, and armed with a little knowledge of how to do it, you can treat snakes for parasites yourself for pennies. The meds are extremely cheap and available OTC. It's getting the dosage right that's critical. For that you need access to a very accurate scale capable of measuring micrograms.

It's hard on a reptile to get dewormed. You're essentially giving them poison. There's a right time and a wrong time to do it. If done properly, it's worth the risk. Your snake will be healthier, have better appetite, better immunity, and will likely live longer and have fewer health issues.

I deworm all my WC snakes as a precaution. There's really no need to spend money on a vet visit and fecal exams when you can pretty much count on a WC snake having parasites. So, I just treat them as if they do have them, and every time, sure enough, they expel pinworms and sometimes tapeworms during treatment. There is almost always a weight gain and improvement in muscle tone and appetite after they are rid of the worms.