I was taking care of a mean snake for a while this summer- he started biting and chewing as his wounds healed and he felt able to protest my presence.

I kept him semi- handleable by gently blowing thru the screen of the cage each time I passed to keep him accustomed to my presence, and by handling him very very briefly (just a quick run thru the fingers while I changed his water and spot cleaned.)I then returned him to his cage with a bit of worm as a reward.

He didn't, in the short time I tended him show any signs of enjoying human contact, but he would tolerate brief contact without violence so long as I kept it brief and kept to routine. Most snakes gradually become more flaxes and willing. To accept humans with time, but there are always exceptionally stubborn individuals.